Welcome to Guo Research Group

Wei Guo, Ph.D.

Associate Professor, Department of Animal and Dairy Sciences, Cardiovascular Research Center, University of Wisconsin-Madison.
Faculty trainer, UW Graduate Program in Cellular and Molecular Biology
Faculty trainer, UW Graduate Program in Molecular and Environmental Toxicology
Faculty trainer, UW Graduate Program in Cellular and Molecular Pathology

The Guo Lab is dedicated to advancing our understanding of posttranscriptional regulation and RNA metabolism in muscle structure and function. Our research focuses particularly on the RBM20–titin pathway and its critical roles in striated muscle biology, encompassing cardiomyopathies, heart failure, and skeletal muscle hypertrophy and regeneration. We employ both in vitro and in vivo models to dissect molecular mechanisms and disease pathways. The long-term goal of the Guo Lab is to develop innovative RNA-based therapeutic strategies aimed at improving human health and enhancing animal production efficiency.

1933 Observatory Dr
Madison, WI 53706